Products / β-Caryophyllene
High-purity sesquiterpene β‑Caryophyllene
Caryophyllene over 95% purity / Refine to the maximum and remove impurities / Derived from Clove (Syzygium aromaticum) / Patent No. 7666803(JP)
Product & Material Overview
β-Caryophyllene is a naturally occurring sesquiterpene found in black pepper, cloves, rosemary, and various other plants. This material is a high-purity β-caryophyllene extracted and refined from cloves (Syzygium aromaticum) using a proprietary technology based on Patent No. 7666803(JP). Conventional clove essential oil contains not only β-caryophyllene but also eugenol and methyl eugenol. Eugenol has an extremely low odor threshold, meaning that even trace amounts can significantly influence the fragrance profile of the final product. Methyl eugenol is also a substance regulated under the standards established by the International Fragrance Association (IFRA). This material has been refined to minimize these impurities to the greatest extent possible, resulting in a high-quality, highly compliant functional ingredient with a standard β-caryophyllene purity of 95% or higher.
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Technical Advantages
- Enhanced Formulation Flexibility Through Eugenol Reduction
A patented manufacturing process significantly reduces eugenol, a compound with a low odor threshold. By maintaining the original aroma characteristics of the ingredient while minimizing interference with blended fragrances and base flavors, this technology enhances flexibility in fragrance and flavor design across a wide range of products.
- Minimizing Methyl Eugenol, an IFRA-Regulated Ingredient
By reducing methyl eugenol content, we have developed raw materials designed to comply with international fragrance regulations. This supports regulatory compliance in the development of cosmetic and fragrance products.
- High-Purity β-Caryophyllene with Purity of 95% or Higher
We offer high-purity β-caryophyllene with a purity of 95% or higher, ensuring consistent quality. Custom specifications with even higher purity levels are also available upon request.
Functional Efficacy Evidence
- Selective binding to the CB2 receptor
β-Caryophyllene has been reported as a natural agonist that selectively binds to the CB2 receptor. Its non-psychoactive mechanism of action, which differs from the psychoactive effects mediated by the CB1 receptor, is attracting attention [1].
- Anti-inflammatory and pain-relieving effects
Cell and animal studies have suggested anti-inflammatory and pain-relieving effects mediated by the CB2 receptor. However, these findings do not necessarily demonstrate the efficacy of the final products containing β-caryophyllene in humans [1][2].
- Insect Behavior and Repellency
Plant-derived terpenes, including β-caryophyllene, are being investigated for applications in insect repellency and behavior control. Practical application requires evaluation of the final formulation under the intended conditions of use, including the target pest species, concentration, formulation, and environmental conditions [3].
- References
[1] Gertsch J. et al . (2008). Proceedings of the National Academy of Sciences , 105(26), 9099–9104. [2] Klauke A.-L. et al. (2014). European Neuropsychopharmacology , 24(4), 608–620. [3] Japanese Patent No. 7220879B1. ( 2023 ).
Potential Application Fields
- Functional Foods and Supplements
By reducing the strong characteristic aroma of clove, this ingredient can be developed into a wide range of food formats, including capsules, tablets, powders, and beverages.
- Cosmetics and Personal Care
Its IFRA-conscious design and low eugenol content enable high-concentration use in products such as perfumes, serums, and creams. It can add value as a functional terpene ingredient while maintaining the original fragrance concept of a brand.
- Daily Consumer Products (Insect repellent and Air Care)
Through high-purity processing, β-caryophyllene can function as an “odorless repellent ingredient” and may be applied in products such as insect repellent sprays, fabric mists, room fragrances, and passive insect control products. It provides functional benefits without compromising the base fragrance profile.
Gallery
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Material Information
Composition: β-Caryophyllene content: NLT 95% (standard specification) Key Features: Low eugenol content (reduces impact on flavor and aroma) Low methyl eugenol content (designed with consideration for IFRA fragrance regulations) Source Material: Derived from clove (Syzygium aromaticum) Intellectual property: Japanese Patent No. 7666803
Disclaimer
This document is based on general scientific knowledge and research reports regarding raw materials and does not guarantee the efficacy or effects of any specific product. The information provided is not intended for the diagnosis, treatment, or prevention of disease, nor does it indicate any medicinal effects. The research data and functional information presented are academic knowledge regarding raw materials or components and do not indicate that similar effects will be obtained in the final product. Research results were obtained under specific conditions, and results may vary depending on the amount used, formulation, and usage environment. In accordance with relevant laws and regulations such as the Pharmaceuticals and Medical Devices Act, the Premiums and Representations Act, and the Health Promotion Act, we avoid expressions that suggest medicinal effects. If you use the contents of this document in product advertising or promotional materials , please check the relevant laws and regulations and ensure appropriate labeling and advertising practices. We are not responsible for any product labeling or advertising expressions based on the contents of this document.